Review Article

Published in:
Volume 7 / Year 2018 / Issue 2

Protein heterogeneity and the immunogenicity of biotherapeutics

Page: 63-9

Abstract: High resolution analytical techniques reveal structural micro-heterogeneity within endogenous proteins, however, they are ‘seen’ as ‘self’ molecules by the immune system and immunological tolerance is established. In contrast the… Read More »

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